Living in areas of high air pollution can lead to decreased cognitive function in older adults, according to new research presented in San Diego at The Gerontological Society of America's (GSA) 65th Annual Scientific Meeting.

This finding is based on data from the U.S. Environmental Protection Agency and the Health and Retirement Study. The analysis was conducted by Jennifer Ailshire, PhD, a National Institute on Aging postdoctoral fellow in the Center for Biodemography and Population Health and the Andrus Gerontology Center at the University of Southern California.

"As a result of age-related declines in health and functioning, older adults are particularly vulnerable to the hazards of exposure to unhealthy air," Ailshire said. "Air pollution has been linked to increased cardiovascular and respiratory problems, and even premature death, in older populations, and there is emerging evidence that exposure to particulate air pollution may have adverse effects on brain health and functioning as well."

This is the first study to show how exposure to air pollution influences cognitive function in a national sample of older men and women. It suggests that fine air particulate matter -- composed of particles that are 2.5 micrometers in diameter and smaller, thought to be sufficiently small that if inhaled they can deposit deep in the lung and possibly the brain -- may be an important environmental risk factor for reduced cognitive function.

The study sample included 14,793 white, black, and Hispanic men and women aged 50 and older who participated in the 2004 Health and Retirement Study (a nationally representative survey of older adults). Individual data were linked with data on 2004 annual average levels of fine air particulate matter from the Environmental Protection Agency's Air Quality System monitors across the country. Cognitive function was measured on a scale of 1 to 35 and consisted of tests assessing word recall, knowledge, language, and orientation.

Ailshire discovered that those living in areas with high levels of fine air particulate matter scored poorer on the cognitive function tests. The association even remained after accounting for several factors, including age, race/ethnicity, education, smoking behavior, and respiratory and cardiovascular conditions.

Fine air particulate matter exposures ranged from 4.1 to 20.7 micrograms per cubic meter, and every ten point increase was associated with a 0.36 point drop in cognitive function score. In comparison, this effect was roughly equal to that of aging three years; among all study subjects, a one-year increase in age was associated with a drop 0.13 in cognitive function score.