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Researchers Investigate Dasatinib in Combination With Other Drugs for Advanced, Recurrent Ovarian Cancer 2012-12-20

By A. A. Secord, D. K. Teoh, W. T. Barry

Researchers at Moffitt Cancer Center and Duke University Medical Center have conducted a phase I trial of dasatinib, an oral SRC-family tyrosine kinase inhibitor, to determine the maximum tolerated dose when combined with paclitaxel and carboplatin

Engineering a Photo-Switch for Nerve Cells in the Eye and Brain 2012-12-20

By Lan Yue, Michal Pawlowski

Chemists and vision scientists at the University of Illinois at Chicago have designed a light-sensitive molecule that can stimulate a neural response in cells of the retina and brain -- a possible first step to overcoming degenerative eye diseases l

PCBs, Other Pollutants May Play Role in Pregnancy Delay 2012-12-20

By Zablotska LB, Bazyka D

Couples with high levels of PCBs and similar environmental pollutants take longer to achieve pregnancy in comparison to other couples with lower levels of the pollutants, according to a preliminary study by researchers at the National Institutes of

A Risk Gene for Cannabis Psychosis 2012-12-20

By Marta Di Forti

The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophreni

Smoking Affects Allergy-Relevant Stem Cells 2012-12-20

By K. Weisse, I. Lehmann

Environmental contaminants, such as smoking, are harmful to the human organism in relation to the occurrence of allergies. This is known. Until now, researchers had never investigated whether and to what extent environmental contaminants also affect

Triclosan in Cosmetics and Personal Care Products Can Increase Allergy Risk 2012-12-20

By R. J. Bertelsen, M. P. Longnecker

Triclosan -- an antibacterial chemical found in toothpaste and other products -- can contribute to an increased risk of allergy development in children. This comes from the Norwegian Environment and Childhood Asthma Study, in which the Norwegian Ins

'Missing Link' Discovered in Defense Mechanism of Tuberculosis Pathogen 2012-12-20

By Koen Van Laer, Lieven Buts

Flemish biologists led by Joris Messens (VIB / Vrije Universiteit Brussel) have discovered that Mycobacterium tuberculosis -- the bacterium that causes tuberculosis -- has an ingenious defence mechanism against oxygen. This knowledge is important in

BPA Shown to Disrupt Thyroid Function in Pregnant Animals and Offspring 2012-12-20

By C. Viguie, S. H. Collet

In utero exposure to bisphenol A (BPA) can be associated with decreased thyroid function in newborn sheep, according to a recent study accepted for publication in Endocrinology, a journal of The Endocrine Society. Hypothyroidism is characterized by

Diabetic Patients Have Higher Prevalence of Hearing Impairment 2012-12-20

By C. Horikawa, S. Kodama

Patients with diabetes have a significantly higher prevalence of hearing impairment than patients without diabetes, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (J

Timing of First Menstual Cycle May Be Predictor of Cardiovascular Disease Risk in Women 2012-12-20

By S. Trikudanathan

Age at onset of menarche (first menstrual cycle) is associated with increased body mass index (BMI), waist circumference, and overall obesity in adulthood, according to a recent study accepted for publication in The Endocrine Society's Journal of Cl

Mobile Phone Services Help Smokers Quit 2012-12-20

By Robyn Whittaker, Hayden McRobbie

Support for quitting smoking via text and video messages can help smokers kick the habit according to a new Cochrane systematic review. The authors of the review found that people were more likely to stay away from cigarettes over a six month period

Cancer: Exercise Reduces Tiredness 2012-12-20

By Fiona Cramp, James Byron-Daniel

Aerobic exercise can help relieve the fatigue often associated with cancer and cancer treatment, according to Cochrane researchers. Their updated systematic review strengthens findings from an earlier version on cancer-related fatigue published in T

Don't Forget to Screen for Diabetes in CAD Patients, Says European Society of Cardiology 2012-12-20

By European Society of Cardiology

While it is well recognized that patients with diabetes are at risk of developing Coronary Artery Disease (CAD), on World Diabetes Day, the European Society of Cardiology (ESC) highlights the fact that patients with CAD are also at great risk of dev

How Threat, Reward and Stress Come Together to Predict Problem Drinking 2012-12-20

By Yuliya S Nikolova, Ahmad R Hariri

Having a drink after a stressful day at work may seem like a natural response for some, but can your neural circuits predict when a drink or two will become problem drinking?

Metals Versus Microbes: The Biocidal Effect of Metalloacid-Coated Surfaces 2012-12-20

By Nathalie Tetault, Houssein Gbaguidi-Haore

A new study published in BioMed Central's open access journal Antimicrobial Resistance and Infection Control reports of a phenomenon that could help control the spread of hospital-acquired infections: a surface-coating of metalloacids kills off micr

Relatives of People Who Die Suddenly from Heart Problems Have Greatly Increased Risk of Cardiovascular Disease 2012-12-20

By M. F. Ranthe, B. G. Winkel

Relatives of young people who have died suddenly from a heart-related problem are at greatly increased risk of developing cardiovascular disease according to a study published online today (Wednesday) in the European Heart Journal.

Bacterial DNA Sequence Used to Map an Infection Outbreak 2012-12-20

By Simon R Harris, Edward JP Cartwright

For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close.

Drug Shrinks Brain Tumors in Children With Tuberous Sclerosis Complex, Study Suggests 2012-12-20

By David Neal Franz

A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce a particular kind of brain tumor in patients with tuberous sclerosis complex (TSC) -- a genetic disease that causes tumors to grow

Reflexology: Ancient Foot Massage Technique May Ease Cancer Symptoms 2012-12-20

By Mei You, David Victorson

A study led by a Michigan State University researcher offers the strongest evidence yet that reflexology -- a type of specialized foot massage practiced since the age of pharaohs -- can help cancer patients manage their symptoms and perform daily ta

First-Of-Its-Kind Program Improves Outcomes for Seniors Admitted for Trauma 2012-12-20

By Magda Lenartowicz, Meredith Parkovnick

A first-of-its-kind program at St. Michael's Hospital lowers risk of delirium in elderly patients admitted for trauma and decreases the likelihood they will be discharged to a long-term care facility.

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