When attacking body cells, bacteria, such as salmonellae or Yersinia (plague pathogens), inject specific bacterial proteins through hollow, syringe-like structures – called injectisomes – into the host cells. These substances reprogram
By Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health
Lymphotoxin is a cytokine, or intercellular messenger, and plays an important role in the immunological balance of the gastrointestinal tract. It regulates the immune system of the digestive tract, which is made up of immune cells, immunoglobulins (antibo
Children with epilepsy are at high risk for depression, anxiety, and behavioral functioning disorders. Mood and behavior are known to change or improve in children following epilepsy surgery, but research is inconsistent concerning the extent of the chang
By Harvard School of Engineering and Applied Sciences
As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists have devised the first method to measure these tiny forces in three-dimensional tissues and living embryos.
To build and maintain muscle strength, it is best for older breast cancer survivors to follow an ongoing exercise program of resistance and impact training. Research has found that the bone benefit from one year of such training could be maintained, even
Resective surgery is an effective treatment for drug-resistant epilepsy. To investigate the effect of epilepsy surgery on patients lives, researchers conducted a long-term retrospective follow up of surgical patients and correlated post-surgical psychosoc
For several years, epilepsy practitioners have questioned the U.S. Food and Drug Administration’s (FDA) definition of bioequivalence as it applies to narrow therapeutic index (NTI) drugs, such as those used for epilepsy. In response to these con
By Perelman School of Medicine at the University of Pennsylvania
Three and a half years after beginning a clinical trial that demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team will today announce the latest results of studies involving both adults a
The management of refractory convulsive status epilepticus (RCSE) varies at different medical centers and from patient to patient. Rapid success in aborting these non-stop seizures is crucial as the risk of neurological damage is high and, though rare, ma
Advanced paternal age has been associated with greater risk for psychiatric disorders, such as schizophrenia and autism. With an increase in paternal age, there is a greater frequency of certain types of mutations that contribute to these disorders in off
Epilepsy patients with complex partial seizures have impaired consciousness during seizure episodes and typically have no memory of the event. However, the mechanisms of seizure unconsciousness are unclear. Research report that the mechanism underlying lo
By American Association for Cancer Research (AACR)
Knowledge about the efficacy of the human papillomavirus (HPV) vaccine in preventing cervical cancer was lacking in the majority of survey respondents for whom the information would be relevant, according to researchers.
Patients with epilepsy often undergo evaluation by concurrent video and EEG monitoring (vEEG) for therapeutic planning, including possible epilepsy surgery. Seizures during monitoring increase the diagnostic yield and requires the withdrawal of anticonvul
Researchers have identified a series of 10 genes that may signify a trifecta of benefits for women diagnosed with ovarian cancer and ultimately reflect improved survival outcomes. The research found that the 10-gene biomarker panel may identify the aggres
By American Association for Cancer Research (AACR)
Women with interruptions in health insurance coverage or with low income levels had a significantly increased likelihood of failing to receive breast cancer care that is in concordance with recommended treatment guidelines, according to researchers.
Three new studies expose the high prevalence of epilepsy and other neurological disorders in US Veterans who served in Operation Enduring Freedom, Operation Iraqi Freedom and Operation New Dawn. The research conducted from these studies indicate that vete
Researchers are one step closer to an eye drop-free reality with the development of a drug-eluting contact lens designed for prolonged delivery of latanoprost, a common drug used for the treatment of glaucoma, the leading cause of irreversible blindness w
Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia (ALL) showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient's immune system.
By European Association for the Study of the Liver
The European Association for the Study of the Liver (EASL) today publishes their revised Clinical Practice Guidelines on the management of hepatitis C virus infection (HCV). The guidelines, which supersede the previous version published in 2011, are desig
By University of North Carolina School of Medicine
Screening to detect medical conditions has become standard practice for many diseases, but insufficient attention has been paid to the potential for harm, according to research conducted.
