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New Drug Target Found for Cystic Fibrosis Lung Disease 2012-12-10

By C. J. Blohmke

Vancouver researchers have discovered the cellular pathway that causes lung-damaging inflammation in cystic fibrosis (CF), and that reducing the pathway's activity also decreases inflammation. The finding offers a potential new drug target for treat

Lack of Vitamin D Contributes to Pain in Black Americans With Knee Osteoarthritis 2012-12-10

By Wiley

A new study reveals that black Americans display lower levels of vitamin D and greater pain sensitivity compared to white Americans. Findings published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), indicate

Protein Reveals Diabetes Risk Many Years in Advance 2012-12-10

By Lund University

When a patient is diagnosed with type 2 diabetes, the disease has usually already progressed over several years and damage to areas such as blood vessels and eyes has already taken place. To find a test that indicates who is at risk at an early stag

Popular Pain Relievers May Reduce Risk of Bladder Cancer 2012-12-10

By Dalsu Baris

Dartmouth researchers have found that duration of ibuprofen use was associated with a reduced risk of bladder cancer in patients in northern New England, which has a high mortality rate of this disease.

Declining Influence of High Impact Factor Journals Documented 2012-12-10

By George A. Lozano

The most prestigious peer-reviewed journals in the world, such as Cell, Nature, Science, and the Journal of the American Medical Association (JAMA), have less and less influence amongst scientists, according to a paper co-authored by Vincent Larivi&

New Insight Into Why Haste Makes Waste 2012-12-10

By Richard P. Heitz, Jeffrey D. Schall

Why do our brains make more mistakes when we act quickly? A new study demonstrates how the brain follows Ben Franklin's famous dictum, "Take time for all things: great haste makes great waste."

New Cell Type Developed for Possible Treatment of Alzheimer's and Other Brain Diseases 2012-12-10

By M. Watanabe

UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

Patients With Heart Block See Strong Benefit from Cardiac Resynchronization Therapy 2012-12-10

By University at Buffalo

Heart failure patients with a condition called "heart block" derive significant benefit from cardiac resynchronization therapy (CRT), according to the results of the Block HF clinical trial, presented November 6 at the American Heart Assoc

Firm Molecular Handshake Needed for Hearing and Balance 2012-12-10

By Marcos Sotomayor

Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart.

Loss of Essential Blood Cell Gene Leads to Anemia 2012-12-10

By Dhvanit I. Shah

Researchers at Brigham and Women's Hospital (BWH) have discovered a new gene that regulates hemoglobin synthesis during red blood cell formation. The findings advance the biomedical community's understanding and treatment of human anemias and mitoch

New Method Helps Link Genomic Variation to Protein Production 2012-12-10

By American Society of Human Genetics

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according to a presentation, No

Head-To-Head Trial of Two Diabetes Drugs Yields Mixed Results 2012-12-10

By John B. Buse

A direct, head-to-head comparison of two of the newer treatments available for type 2 diabetes yielded mixed results.

Breast Cancer Drug Could Halt Other Tumors 2012-12-10

By Alexander F. Bruns

The drug, geldanamycin, is well known for attacking a protein associated with the spread of breast cancer. However, a laboratory-based study found it also degraded a different protein that triggers blood vessel growth.

Stay in Bed or Feel the Burn? What to Do When You Are Sick 2012-12-10

By Loyola University Health System

Stuffy noses, hacking coughs and aches all over -- cold and flu season has arrived. Though your body may be aching and your nose running like a faucet, it can be difficult to decide if you should continue your exercise routine or take a temporary br

Discovery May Help Nerve Regeneration in Spinal Injury 2012-12-10

By University of Liverpool

Scientists at the Universities of Liverpool and Glasgow have uncovered a possible new method of enhancing nerve repair in the treatment of spinal cord injuries.

Leisure-Time Physical Activity Extends Life Expectancy as Much as 4.5 Years 2012-12-10

By Steven C. Moore

Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the National Cancer Institute (NCI), part of the

Simpler Way to Predict Heart Failure 2012-12-10

By Methodist Hospital

The most widely used models for predicting heart failure rely on a complex combination of lifestyle, demographic, and cardiovascular risk factor information.

Small Change in Defibrillator Therapy Leads to Huge Benefits for Heart Patients 2012-12-10

By Arthur J. Moss

A new study shows that defibrillators -- devices designed to detect and correct dangerous heart rhythms -- can help people with heart disease live longer, and with a much better quality of life, than they do now.

Anti-Tobacco Policies Responsible for Brazil's Big Success in Reducing Smoking Rates 2012-12-10

By David Levy, Liz Maria de Almeida, Andre Szklo

Smoking rates in Brazil have dropped by half over the past two decades thanks to strict tobacco control policies, according to a study by US and Brazilian researchers published in this week's PLOS Medicine.

Synthetic Biofilter Removes Estrogens from Drinking Water 2012-12-10

By University of Bielefeld

Conventional methods of filtering waste water in sewage treatment plants are unable to completely remove medicine residues such as the estrogens in birth control pills. These residues then find their way into rivers and lakes and also accumulate in

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