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BRCA Mutations May Be 'Achilles' Heel' for Some Metastatic Breast Cancers 2012-09-28

By Methodist Hospital, Houston

Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an investigational drug believed to hamper cancer&

A Carefully Scheduled High-Fat Diet Resets Metabolism and Prevents Obesity, Researchers Find 2012-09-28

By H. Sherman

New research from the Hebrew University of Jerusalem shows that a carefully scheduled high-fat diet can lead to a reduction in body weight and a unique metabolism in which ingested fats are not stored, but rather used for energy at times when no foo

What's the Main Cause of Obesity -- Our Genes or the Environment? 2012-09-28

By T. M. Frayling

The ongoing obesity epidemic is creating an unprecedented challenge for healthcare systems around the world, but what determines who gets fat? Two experts debate the issue on bmj.com today.

People Who Read Food Labels Stay Thinner, Study Finds 2012-09-27

By Maria L. Loureiro

An international team of scientists headed from the University of Santiago de Compostela has found that reading the labels on food products is linked to obesity prevention, especially in women. According to the study which used data from the United

Guidelines Help Family Physicians Evaluate, Manage Urinary Incontinence for Women 2012-09-25

By Abigail Lowther

Millions of women experience a loss of bladder control, or urinary incontinence, in their lifetime.

Researchers Find Novel Predictor for MDS Progression Risk 2012-09-25

By A. W. Mailloux

Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) to acute myeloid leukemia.

Shine and Rise: Light-Activated Reversal of Anesthesia 2012-09-25

By Marco Stein

In a new study, a light-sensitive moiety has been added to propofol, a commonly used anesthetic, allowing its narcotic effect to be controlled by light. The compound also offers a possible route to the treatment of certain eye diseases.

Low Ghrelin: Reducing Appetite at the Cost of Increased Stress? 2012-09-25

By Sarah J. Spencer

Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied

Mild Increases in Thyroid-Stimulating Hormone Not Harmful in the Elderly 2012-09-25

By Avantika C. Waring

There is no evidence to link mildly elevated thyroid-stimulating hormone (TSH) levels to an increase in mortality among the elderly, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology &a

Gestational Exposure to Urban Air Pollution Linked to Vitamin D Deficiency in Newborns 2012-09-25

By Endocrine Society

Gestational exposure to ambient urban air pollution, especially during late pregnancy, may contribute to lower vitamin D levels in offspring, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocri

First Comprehensive Review of European Breast Cancer Screening Programs Finds Benefits Outweigh Harm 2012-09-25

By Queen Mary, University of London

A major review of breast cancer screening services in Europe, jointly led by researchers at Queen Mary, University of London, has concluded that the benefits of screening in terms of lives saved outweigh the harms caused by over-diagnosis.

Antidepressants, Sleeping Pills and Anxiety Drugs May Increase Driving Risk 2012-09-25

By Chia Ming-Chang

Drugs prescribed to treat anxiety, depression and insomnia may increase patients' risk of being involved in motor vehicle accidents, according to a recent study, published in the British Journal of Clinical Pharmacology. Based on the findings, the r

Protection Against Whooping Cough Waned During the Five Years After Fifth Dose of DTaP 2012-09-25

By Nicola P. Klein

Protection against whooping cough (also called pertussis) waned during the five years after the fifth dose of the combined diphtheria, tetanus, acellular pertussis (DTaP) vaccine, according to researchers from the Kaiser Permanente Vaccine Study Cen

Single Gene Cause of Insulin Sensitivity May Offer Insight for Treating Diabetes 2012-09-25

By Aparna Pal

The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.

Expert Recommendations Ignore Vital Issues for Patients, Study Suggests 2012-09-25

By Pamela Hartzband

In the medical world, where decisions invariably involve risk and uncertainty, two Beth Israel Deaconess Medical Center physicians note that experts generally base their recommendations on the outcome of death, which is "readily determined, eas

Belly Button Kidney Removal Boosts Living-Donor Satisfaction 2012-09-25

By Rolf N. Barth

In the largest study of its kind, living donors who had a kidney removed through a single port in the navel report higher satisfaction in several key categories, compared to donors who underwent traditional multiple-port laparoscopic removal.

Novel Non-Antibiotic Agents Against MRSA and Strep Infections 2012-09-25

By Case Western Reserve University

Menachem Shoham, PhD, associate professor of biochemistry at Case Western Reserve University School of Medicine, has discovered novel antivirulence drugs that, without killing the bacteria, render Methicillin Resistant Staphylococcus Aureus (MRSA) a

Sinusitis Linked to Microbial Diversity 2012-09-25

By N. A. Abreu

A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according

Scientists Discover How an Out-Of-Tune Protein Leads to Muscle Demise in Heart Failure 2012-09-25

By Johns Hopkins Medicine

A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.

Smoking Abstinence Tough for Teens, Too 2012-09-25

By Brown University

A new study finds that relatively early into tobacco addiction, teens experience many of the same negative psychological effects during abstinence as adults do, with a couple of exceptions. The data can inform efforts to improve the efficacy of quit

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