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Doing the Math to Fight Childhood Obesity 2012-08-15

By Columbia University's Mailman School of Public Health

Dieters often use online calorie calculators to stay true to their weight-loss plan. Translating the concept to the population health arena, researchers at Columbia University's Mailman School of Public Health created the Caloric Calculator to help

Acute Stress Alters Control of Gene Activity: Researchers Examine DNA Methylation 2012-08-15

By E Unternaehrer

Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum together with colleagues from Basel, Trier and London for the first time in the journal Transl

Vaccine Targets Malignant Brain Cancer Antigens, Significantly Lengthens Survival 2012-08-15

By Surasak Phuphanich

An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online Aug.

Babies May Not Have a 'Moral Compass' After All 2012-08-15

By Damian Scarf

New research from New Zealand's University of Otago is casting doubt on a landmark US study that suggested infants as young as six months old possess an innate moral compass that allows them to evaluate individuals as 'good' or 'bad'.

Karate Black Belts' White Matter Shows How a Powerful Punch Comes from the Brain 2012-08-15

By R. E. Roberts

Brain scans have revealed distinctive features in the brain structure of karate experts, which could be linked to their ability to punch powerfully from close range. Researchers from Imperial College London and UCL (University College London) found

New Drug Target for Schizophrenia Identified 2012-08-15

By Mitsumasa Kurita

Researchers at Mount Sinai School of Medicine may have discovered why certain drugs to treat schizophrenia are ineffective in some patients. Published online in Nature Neuroscience, the research will pave the way for a new class of drugs to help tre

Three Continents, One Gene: DNA Detectives Track Down Nerve Disorder Cause 2012-08-15

By Yi-chung Lee

A global hunt for the cause of a crippling inherited nerve disorder has found its target. The discovery opens the door for better diagnosis and treatment of this particular disease -- but also for better understanding of why nerves in the brain's mo

Human Embryos Frozen for 18 Years Yield Viable Stem Cells Suitable for Biomedical Research 2012-08-15

By Kamthorn Pruksananonda

Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research. Prolonged e

Key Culprit Causing Muscle Atrophy Identified 2012-08-15

By S. M. Ebert

Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle -- even slight or gradual -- is about as common to the human condition as breathing.

Diabetes Drugs Prescribed to More Than 15 Million Americans Raises Risk of Bladder Cancer 2012-08-15

By R. Mamtani

A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of

Butter Flavoring Ingredient in Microwave Popcorn, Thought Safe for Food Industry Workers, Is a Respiratory Hazard 2012-08-15

By Ann Hubbs

The ingredient 2,3-pentanedione (PD), used to impart the flavor and aroma of butter in microwave popcorn, is a respiratory hazard that can also alter gene expression in the brain of rats. Manufacturers started using PD when another butter flavoring,

Scientists Use Light to 'Tag and Track' Genetic Processes 2012-08-15

By MJ Shoura

In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material in some types of cells.

Existing Drugs Offer New Treatment Options for High-Risk Childhood Leukemia Subtype 2012-08-15

By Kathryn G. Roberts

Discovery of the genetic basis of a high-risk subtype of leukemia shows some patients might benefit from existing targeted therapies, advancing the goal of curing all children with the most common childhood cancer

New Class of Proteins Allows Breast Cancer Cells to Evade Tyrosine Kinase Inhibitors 2012-08-15

By Rocky Cipriano

Aberrant regulation of cell growth pathways is required for normal cells to become cancerous, and in many types of cancer, cell growth is driven by a group of enzymes known as receptor tyrosine kinases (RTKs). The RTK epidermal growth factor recepto

Common Antibiotics Pose a Rare Risk of Severe Liver Injury in Older Patients 2012-08-15

By BVB Reddy

The commonly used broad-spectrum antibiotics moxifloxacin and levofloxacin are associated with an increased risk of severe liver injury in older people, according to a new study published in CMAJ (Canadian Medical Association Journal).

Protein That Helps Tumor Blood Vessels Mature Could Make Cancer Drugs More Effective 2012-08-15

By Junko Sawada

To survive, tumors need blood supply to provide them with nutrients and oxygen. To get that supply, cancer cells stimulate new blood vessel growth -- a process called tumor angiogenesis.Many attempts have been made to inhibit this process as a means

New Therapy Prevents Lung Cancer Growth in Mice 2012-08-15

By Antonio Maraver

The discovery, which is already being tested in co-clinical trials, brings new clues for the treatment of this disease.

New Key Element Discovered in Pathogenesis of Burkitt Lymphoma 2012-08-15

By Sandrine Sander

Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system. Now Dr. Sandrine Sander and Professor

Gene Discovery Could Improve Treatment for Acute Myeloid Leukemia 2012-08-15

By Masahiro Kawahara

Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a step closer to new treatmen

Chromosomal Translocations Point the Way Toward Personalized Cancer Care 2012-08-15

By Jing H. Wang

A broken chromosome is like an unmoored beansprout circling in search of attachment. If a cell tries to replicate itself with broken chromosomes, the cell will be killed and so it would very much like to find its lost end. Often, it finds a workable

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