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How Embryonic Stem Cells Orchestrate Human Development 2012-04-13

By Yale University

Yale researchers show in detail how three genes within human embryonic stem cells regulate development, a finding that increases understanding of how to grow these cells for therapeutic purposes.

Rapid Method of Assembling New Gene-Editing Tool Could Revolutionize Genetic Research 2012-04-13

By Massachusetts General Hospital

Development of a new way to make a powerful tool for altering gene sequences should greatly increase the ability of researchers to knock out or otherwise alter the expression of any gene they are studying. The new method allows investigators to quic

Black Flies May Have a Purpose After All 2012-04-13

By UGA College of Agricultural and Environmental Sciences

Black flies drink blood and spread disease such as river blindness-creating misery with their presence. A University of Georgia study, however, proves that the pesky insects can be useful.

'Nanobubbles' Plus Chemotherapy Equals Single-Cell Cancer Targeting 2012-04-13

By Rice University

Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) are developing new methods to

Manipulating the Immune System to Develop 'Next-Gen' Vaccines 2012-04-13

By Walter and Eliza Hall Institute

The discovery of how a vital immune cell recognises dead and damaged body cells could modernise vaccine technology by 'tricking' cells into launching an immune response, leading to next-generation vaccines that are more specific, more effective and

New Stem Cell Line Provides Safe, Prolific Source for Disease Modeling and Transplant Studies 2012-04-13

By Children's Hospital of Philadelphia

Researchers have generated a new type of human stem cell that can develop into numerous types of specialized cells, including functioning pancreatic beta cells that produce insulin. Called endodermal progenitor (EP) cells, the new cells show two imp

Heightened Sensitivity to Cheap, High-Calorie Food Is Linked With Obesity 2012-04-12

By Cell Press

Obesity is increasing worldwide in adults and children and is currently viewed by many as one of the most serious threats to public health. It is likely that solutions to the obesity pandemic will require changes in public policy and that scientific

To Prevent Leukemia's Dreaded Return, Go for the Stem Cells 2012-04-12

By Cell Press

Researchers reporting in the April Cell Stem Cell, a Cell Press publication, have found a way to stop leukemia stem cells in their tracks. The advance in mice suggests that a combination approach to therapy might stamp out chronic myeloid leukemia (

Nature and Nurture: Discovery Sheds New Light On Congenital Birth Defects 2012-04-12

By Arizona State University College of Liberal Arts and Sciences

Scientists have made a landmark discovery that could help women minimize or even avoid the risk of having a baby born with congenital birth defects. The study is published April 5 in the international journal Cell.

Disarming Disease-Causing Bacteria 2012-04-12

By Monash University

New treatments that combat the growing problem of antibiotic resistance by disarming rather than killing bacteria may be on the horizon, according to a new study.

RV144 HIV Vaccine Trial Give Clues About Protection from HIV 2012-04-12

By Duke University Medical Center

Researchers have gained important clues about immune system responses that could play a role in protecting people from HIV infection in follow-up studies from the world's largest HIV vaccine trial to date. Results from laboratory studies based on th

Microflora Have Decisive Role With Autoimmune Illnesses, Some Good, Some Bad 2012-04-12

By Charite - Universitatsmedizin Berlin

When the right microorganisms are at work, immune cells involved in the development of autoimmune illnesses like psoriasis, multiple sclerosis and arthritis, can develop anti-inflammatory properties. Scientists at Charité -- Universitäts

Handheld Plasma Flashlight Rids Skin of Notorious Pathogens 2012-04-12

By Institute of Physics

A group of Chinese and Australian scientists have developed a handheld, battery-powered plasma-producing device that can rid skin of bacteria in an instant.

Possible Clues Found to Why HIV Vaccine Showed Modest Protection 2012-04-12

By NIH/National Institute of Allergy and Infectious Diseases

Insights into how the first vaccine ever reported to modestly prevent HIV infection in people might have worked were recently published online in the New England Journal of Medicine. Scientists have found that among adults who received the experimen

Antipsychotic Drug May Be Helpful Treatment for Anorexia Nervosa 2012-04-12

By University of Chicago Medical Center

Low doses of a commonly used atypical antipsychotic drug improved survival in a mouse model of anorexia nervosa, University of Chicago researchers report this month. The result offers promise for a common and occasionally fatal eating disorder that

Eating Flavonoids Protects Men Against Parkinson's Disease, Study Finds 2012-04-12

By University of East Anglia

Men who eat flavonoid-rich foods such as berries, tea, apples and red wine significantly reduce their risk of developing Parkinson's disease, according to new research by Harvard University and the University of East Anglia.

Antibody Therapy Prevents Gastrointestinal Damage Following Radiation Exposure in Mice 2012-04-12

By Memorial Sloan-Kettering Cancer Center

A new study offers the first evidence of a drug capable of preventing lethal damage to the gastrointestinal (GI) tract caused by exposure to high levels of ionizing radiation, such as those occurring during a nuclear incident. There are currently no

Memory Declines Faster in Years Closest to Death; Mental Activity Best Protection 2012-04-12

By American Academy of Neurology

New research finds that a person's memory declines at a faster rate in the two- and-a-half years before death than at any other time after memory problems first begin. A second study shows that keeping mentally fit through board games or reading may

First Targeted Nanomedicine to Enter Human Clinical Studies 2012-04-12

By Brigham & Women's Hospital

A team of scientists, engineers and physicians from Brigham and Women's Hospital (BWH), Dana-Farber Cancer Institute (DFCI), Harvard Medical School (HMS), Massachusetts Institute of Technology (MIT), BIND Biosciences, Translational Genomics Research

Injectable Contraceptives Linked to Breast Cancer Risk in Younger Women 2012-04-12

By Fred Hutchinson Cancer Research Center

The first large-scale U.S.-based study to evaluate the link between an injectable form of progestin-only birth control and breast cancer risk in young women has found that recent use of a year or more doubles the risk. The results of the study, led

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