By University of Southern California, Keck School of Medicine
Scientists have genetically engineered a mouse to more closely mimic a human immune response. The transgenic mouse exhibits humanized CD1d molecules, naturally occurring molecules that activate an especially potent white blood cell called the natural kill
By Columbia University's Mailman School of Public Health
Obesity kills, giving rise to a host of fatal diseases. But when it comes to seniors, a slew of research has reported an "obesity paradox" that says, at age 65 and older, an elevated BMI won't shorten your lifespan, and may even extend it. A new
Among older women, getting a mammogram every two years was just as beneficial as getting a mammogram annually, and led to significantly fewer false positive results, according to a new study.
Scientists have identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent
Researchers have identified a clutch of cells that -- if seen in a male patient's blood after receiving a brand-new immune system in the form of a bone-marrow transplant from a female donor -- herald the onset of chronic graft-versus-host disease, or cGVH
Patients who experience chest pain in the 24 hours preceding a heart attack, also called preinfarction angina, have smaller heart attacks and improved cardiac function in the contemporary cardiac stenting era, researchers found.
Plant and animal cells contain two genomes: One in the nucleus and one in the mitochondria. When mutations occur in each, they can become incompatible, leading to disease. To increase understanding of such illnesses, scientists have traced one example in
Around one in ten young teens with mental health issues also drinks alcohol, smokes cigarettes, and uses cannabis on a weekly basis, indicates Australian research.
Mutations which affect the gene ASXL3 cause a novel syndrome similar to Bohring-Opitz syndrome, finds a a new study. This molecular definition distinguishes these children from those with Bohring-Opitz, and other similar syndromes, and highlights a techni
Researchers have overcome a major challenge to treating brain diseases by engineering an experimental molecular therapy that crosses the blood-brain barrier to reverse neurological lysosomal storage disease in mice. Scientists say the study provides a non
A team of researchers from Scotland has used a novel 3-D printing technique to arrange human embryonic stem cells for the very first time. Scientists hope that this breakthrough will allow three-dimensional tissues and structures to be created using hESCs
Regular exposure to sunlight -- specifically ultraviolet B -- may reduce the risk of developing rheumatoid arthritis, indicates a large long-term study.
Researchers have devised a way to detect whether cells previously transplanted into a living animal are alive or dead, an innovation they say is likely to speed the development of cell replacement therapies for conditions such as liver failure and type 1
A team of researchers has discovered that amyloid peptides are harmful to the blood vessels that supply the brain with blood in Alzheimer's disease -- thus accelerating cognitive decline by limiting oxygen-rich blood and nutrients. In their animal studies
A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second
By Louisiana State University Health Sciences Center
In a new study, researchers report that hearing and balance can be rescued by a new therapy in a mouse model of Usher syndrome (Usher) that contains the mutation responsible for type 1C Usher. The results provide the first evidence that congenital deafnes
The underlying medical conditions facing young adults who undergo computed tomography (CT) exams represent a significantly greater health risk than that of radiation-induced cancer from CT, according to a new study.
By Helmholtz Association of German Research Centres
MALAT1, an RNA molecule, is a marker for progression of lung cancer. Researchers have now found out that MALAT1 activates metastasis-promoting genes in cancer cells. In mice, blocking of MALAT1 reduced the number and size of lung cancer metastases.
A new study found no evidence to support concerns that abnormal neurodegenerative disease proteins are "infectious" or transmitted from animals to humans or from one person to another.
