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Kidney Tumors Have a Mind of Their Own 2012-12-30

By A. H. Girgis, V. V. Iakovlev

Kidney tumours may be smarter than we thought. New research has found there are several different ways that kidney tumours can achieve the same result -- namely, grow.

Potential Drug Target for Inflammatory Diseases Including Cancers 2012-12-30

By Arkasubhra Ghosh, Gaye Saginc

A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodeg

Mechanism to Repair Clumped Proteins Explained 2012-12-30

By Fabian Seyffer, Eva Kummer

Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Heidelberg researchers have now decrypted the fundamental mechanism for dissolving

Six Steps to Reduce Dementia's Most Troubling Symptoms 2012-12-30

By Johns Hopkins University School of Nursing

Behavior changes are among the most visible, disruptive and distressing symptoms of Alzheimer's disease and other dementias. From confusion, repetitive questioning and combativeness to wandering, hallucinations and loss of inhibition, the symptoms c

Novel Mechanism Through Which Normal Stromal Cells Become Cancer-Promoting Stromal Cells Identified 2012-12-30

By Anirban K. Mitra, Marion Zillhardt

New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to data published i

Inhaled Nitric Oxide Improves Outcomes in Mice Resuscitated With Stored Blood 2012-12-30

By Chong Lei, Binglan Yu, Mohd Shahid

Inhaled nitric oxide reduced the adverse effects of transfusing stored blood in mice, according to a study from the December issue of Anesthesiology. Researchers found that inhaled nitric oxide reduced tissue injury and improved short-term survival

MRI Shows Brain Disruption in Patients With Post-Concussion Syndrome 2012-12-29

By Radiological Society of North America

MRI shows changes in the brains of people with post-concussion syndrome (PCS), according to a new study published online in the journal Radiology. Researchers hope the results point the way to improved detection and treatment for the disorder.

Diabetes Drug Improves Memory, Study Suggests 2012-12-29

By University of Texas Medical Branch at Galveston

An FDA-approved drug initially used to treat insulin resistance in diabetics has shown promise as a way to improve cognitive performance in some people with Alzheimer's disease.

New Test for Tuberculosis Could Improve Treatment, Prevent Deaths in Southern Africa 2012-12-29

By Nicolas A. Menzies, Ted Cohen

A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common -- according to a new study by Harvard School of Public

More Work Needed On Models to Predict Risk of Chronic Kidney Disease 2012-12-29

By Justin B. Echouffo-Tcheugui, Andre P. Kengne

Models used for predicting the likelihood of individuals developing chronic kidney disease and for predicting disease progression in people who already have the condition are useful tools but not yet robust enough to help inform clinical guidelines,

Evolution of Human Intellect: Human-Specific Regulation of Neuronal Genes 2012-12-29

By Hennady P. Shulha, Jessica L. Crisci

A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons.

Beneficial Microbes Are 'Selected and Nurtured' in the Human Gut 2012-12-29

By Jonas Schluter, Kevin R. Foster

Animals, including humans, actively select the gut microbes that are the best partners and nurture them with nutritious secretions, suggests a new study led by Oxford University, and published November 20 in the open-access journal PLOS Biology.

Human Obedience: The Myth of Blind Conformity 2012-12-29

By S. Alexander Haslam, Stephen. D. Reicher

In the 1960s and 1970s, classic social psychological studies were conducted that provided evidence that even normal, decent people can engage in acts of extreme cruelty when instructed to do so by others. However, in an essay published November 20 i

Nearly 90 Percent of Clinical Trialists Think Data Should Be More Easily Shared 2012-12-29

By V. Rathi, K. Dzara, C. P. Gross

Nearly nine out of ten clinicians carrying out biomedical research trials believe that trial data should be shared more easily, even though they do express some practical concerns, a study published on the British Medical Journal website.

Low Muscle Strength in Adolescence Linked to Increased Risk of Early Death 2012-12-29

By F. B. Ortega, K. Silventoinen

Low muscle strength in adolescence is strongly associated with a greater risk of early death from several major causes, suggests a large study published on the British Medical Journal website.

Trial Results 'Do Not Support the Use of General Health Checks,' Warn Experts 2012-12-29

By L. T. Krogsboll, K. J. Jorgensen

Researchers have found that routine general health checks, which have become common practice in some countries, do not reduce the number of deaths from cardiovascular disease or cancer. They do, however, increase the number of new diagnoses.

Discovery Offers New Treatment for Epilepsy 2012-12-29

By Pishan Chang, Nicole Terbach

New drugs derived from components of a specific diet used by children with severe, drug-resistant epilepsy could offer a new treatment, according to research published today in the journal Neuropharmacology.

IUDs Don't Cause Pelvic Inflammatory Disease in Women, Experts Say 2012-12-29

By Sufrin, Carolyn B.; Postlethwaite, Debbie

The risk of developing pelvic inflammatory disease (PID) following insertion of an intrauterine device (IUD) is very low, whether or not women have been screened beforehand for gonorrhea and chlamydia, according to a joint study of nearly 60,000 wom

Adenotonsillectomy May Help Resolve Obstructive Sleep Apnea in Children With Prader-Willi Syndrome 2012-12-29

By Stacy L. Meyer et al

Children with Prader-Willi syndrome may receive relief from sleep disorders after undergoing an adenotonsillectomy, suggests a new study from Nationwide Children's Hospital published in the November print issue of the Archives of Otolaryngology-Head

Natural Fungus May Provide Effective Bed Bug Control 2012-12-29

By Alexis M. Barbarin, Nina E. Jenkins

"Don't let the bedbugs bite" is no longer a harmless adage. In reality today, these bloodthirsty bugs infest thousands of homes. According to a team of Penn State entomologists, biopesticides -- naturally occurring microorganisms -- might

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