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Genetic Test Results for Lynch Syndrome Improved With New Computer Program 2012-12-07

By Bryony Thompson

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance." This can be a problem, as people with Lynch syndrome hav

New Target Discovered for Food Allergy Treatment 2012-12-07

By Meiqin Wang

Researchers at National Jewish Health have discovered a novel target for the treatment of food allergies. Erwin Gelfand, MD, and his colleagues report in the October 2012 issue of the Journal of Allergy and Clinical Immunology that levels of the enz

A Protein's Role in Helping Cells Repair DNA Damage 2012-12-07

By University at Buffalo

In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.

Caffeine's Effect On the Brain's Adenosine Receptors Visualized for the First Time 2012-12-07

By Society of Nuclear Medicine

Molecular imaging with positron emission tomography (PET) has enabled scientists for the first time to visualize binding sites of caffeine in the living human brain to explore possible positive and negative effects of caffeine consumption. According

Novel Technique to Produce Stem Cells from Peripheral Blood 2012-12-07

By The Journal of Visualized Experiments

Stem cells are a valuable resource for medical and biological research, but are difficult to study due to ethical and societal barriers. However, genetically manipulated cells from adults may provide a path to study stem cells that avoid any ethical

Feedback Loop Maintains Basal Cell Population 2012-12-07

By Joseph M. Valdez

Notch -- the protein that can help determine cell fate -- maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein TGF beta (transforming growth factor beta), said Baylor College o

Male Fertility Can Be Restored After Cancer Treatment, Researchers Find 2012-12-07

By Brian P. Hermann

An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and Magee-Womens Research Instit

Gene Required for Nerve Regeneration Identified 2012-12-07

By Michelle C. Stone

A gene that is associated with regeneration of injured nerve cells has been identified by scientists at Penn State University and Duke University. The team, led by Melissa Rolls, an assistant professor of biochemistry and molecular biology at Penn S

Living Donors Fare Well Following Liver Transplantation, Study Finds 2012-12-07

By Leona Kim-Schluger, Sander Florman

Researchers in Japan report that health-related quality of life (HRQOL) for donors following living donor liver transplantation (LDLT) was better than the general Japanese population (the norm). This study -- one of the largest to date -- found that

Toilet Training Methods Not Responsible for Differences in Volume of Urinary Accidents 2012-12-07

By Marc Colaco

Parents: stop worrying about which toilet training method to use -- where urinary accidents in children are concerned, it doesn't matter. This clearly-stated message, published November 1in Clinical Pediatrics by physician researchers from the Unive

Targeting Drugs With Hydrogels 2012-12-07

By Prapatsorn Techawanitchai

Researchers in Japan have developed a technique which allows them to control and target drug delivery to specific sites of the body at specific times, thus reducing side effects and improving treatment dramatically.

Scientists Create 'Endless Supply' of Myelin-Forming Cells 2012-12-07

By C. R. McClain

In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potenti

Computational Medicine Enhances Way Doctors Detect, Treat Disease 2012-12-07

By RL Winslow

Computational medicine, a fast-growing method of using computer models and sophisticated software to figure out how disease develops -- and how to thwart it -- has begun to leap off the drawing board and land in the hands of doctors who treat patien

Adding Soy to Diet Does Not Affect Onset of Menopausal Hot Flashes 2012-12-07

By Ellen B. Gold

A team of investigators led by UC Davis found that eating soy products such as soy milk and tofu did not prevent the onset of hot flashes and night sweats as women entered menopause.

Sleep Problems Cost Billions 2012-12-07

By University of Bergen

Insomnia and sleep apnea are turning us into major health service consumers, causing us to be less productive at work, and may even lead to serious accidents.

Cellular Landscaping: Predicting How, and How Fast, Cells Will Change 2012-12-07

By DR Sisan

A research team at the National Institute of Standards and Technology (NIST) has developed a model for making quantifiable predictions of how a group of cells will react and change in response to a given environment or stimulus -- and how quickly. T

Toward Making Replacement Organs: Scientists Learn How to Unlock the Destiny of a Cell 2012-12-07

By UC Santa Barbara

Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell. The findings could lead to new ways of making replacement organs.

High Blood Cholesterol Is Overlooked 2012-12-07

By Marianne Benn

High blood cholesterol, a serious hereditary disease, is far more common than previously recognised and not treated sufficiently. This is shown in new research from the University of Copenhagen and Herlev Hospital, and the results have recently been

Meth Vaccine Shows Promising Results in Early Tests; Blocking a Meth High Could Help Addicts Committed to Recovery 2012-12-07

By Michelle L. Miller

Scientists at The Scripps Research Institute (TSRI) have performed successful tests of an experimental methamphetamine vaccine on rats. Vaccinated animals that received the drug were largely protected from typical signs of meth intoxication. If the

Intensified Antibiotic Treatment for Tuberculous Meningitis 2012-12-07

By Rovina Ruslami

Researchers from the Radboud UMC have conducted the first study globally to show that intensified antibiotic treatment can improve the prognosis of patients with tuberculous (TB) meningitis, the most severe form of TB which carries a mortality of up

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