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Cancer Bound: How Some Carcinogens Evade Removal by Stabilizing the Very DNA They Attack 2012-12-07

By University of Texas at Austin, Texas Advanced Computing Center

A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette smoke, and are part of any barbequed

New Finding Gives Clues for Overcoming Tamoxifen-Resistant Breast Cancer 2012-12-07

By University of Cincinnati Academic Health Center

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespr

When Considering Bariatric Surgery, Think About Bones 2012-12-07

By Garvan Institute of Medical Research

Bariatric surgery, which significantly curtails the amount of food a person can eat, is the most effective treatment against obesity and is being recognized as a potentially valuable tool in the fight against diabetes related to obesity. It is being

Tumor-Causing Cells Are Squishier 2012-12-07

By Methodist Hospital, Houston

A new tool developed by scientists at The Methodist Hospital separates tumor-causing cancer cells from more benign cells by subjecting the cells to a microscopic game of Plinko -- except only the squishiest cells make it through.

Active Surveillance Can Reduce Suffering Among Men With Prostate Cancer 2012-12-07

By University of Gothenburg

With active surveillance many men with prostate cancer could dispense with radiation treatment and surgery, and thus avoid adverse effects such as incontinence and impotence. This is the outcome of a study of almost 1,000 men diagnosed with prostate

Trickle-Down Anxiety: Study Examines Parental Behaviors That Create Anxious Children 2012-12-07

By Meghan Crosby Budinger

Parents with social anxiety disorder are more likely than parents with other forms of anxiety to engage in behaviors that put their children at high risk for developing angst of their own, according to a small study of parent-child pairs conducted a

Regular Physical Activity Reduces Risk of Dementia in Older People 2012-12-07

By Ana Verdelho et al

Regular physical activity may help older people reduce their chances of getting dementia.

Combination Treatment May Improve Survival of Breast Cancer Patients With Brain Metastases 2012-12-07

By Massachusettes General Hospital

Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospita

New Light On the Genetic Basis of Inflammatory Diseases 2012-12-07

By Montreal Heart Institute

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD). Crohn's disease and ulcerative colitis, the two most common forms of IB

New Target for Lung Cancer Treatment Identified 2012-12-07

By JM Tuscano

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of

Promising Therapy Developed for Huntington's Disease 2012-12-07

By DOE/Lawrence Berkeley National Laboratory

There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms o

Health of Kidney Disease Patients: Diet and Blood Pressure 2012-12-07

By American Society of Nephrology

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on diet and blood pressure in kidney disease patients.

Researchers Use Blood Testing to Predict Level of Enzymes That Facilitate Disease Progression 2012-12-07

By Georgia Institute of Technology Research News

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult. In a new study, researchers took another step toward that goal by developing a technique able to predict from a blood sampl

Researchers Target Breast Cancer in Three Trials 2012-12-07

By George Mason University

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

Antibiotics Observed Attacking Tuberculosis: Mass Spectrometry Shows Scientists How Antibiotics Function Inside Living Bacteria 2012-12-07

By Weill Cornell Medical College

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells

New Therapeutic Target for Alzheimer's Disease Identified 2012-12-07

By Rongqing Chen

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease.

First Effective Treatment of Tumors Arising from Common Genetic Disease NF1, Suggested by Study 2012-12-07

By Kent A. Robertson

Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.

Gene Switch Important in Cancer Discovered 2012-12-07

By Inderpreet Kaur Sur

Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published in Science,

Laser-Light Testing of Breast Tumor Fiber Patterns Helps Show Whose Cancer Is Spreading 2012-12-07

By Johns Hopkins Medicine

Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue

Experimental Therapy for Emphysema Tested 2012-12-07

By University of Alabama at Birmingham

Researchers at the University of Alabama at Birmingham injected a foam sealant into the lungs of a former smoker on Oct. 29, 2012, to treat his worsening emphysema. He was the first patient in the United States treated in a late-stage clinical trial

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