By Brigham and Women's Hospital
Researchers have found that some patients who receive generic drugs that vary in their color are over 50 percent more likely to stop taking the drug, leading to potentially important and potentially adverse clinical effects.
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By University of Utah Health Sciences
Researchers have discovered that adding lovastatin, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of cerebral malaria.
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By University of Edinburgh
Scientists have shed light on why some people are more susceptible to gout than others. A study has identified 18 new genetic variations that increase levels of uric acid in the blood, which is the main cause of the disease. High levels of uric acid form
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By Libre de Bruxelles, Universit
Researchers have uncovered a novel role of BRCA1 in regulating the survival of skin stem cells. Our DNA, which stores our genetic information, is constantly submitted to damage. If not properly repaired, DNA damage can lead to cell death, which may in tur
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By Brown University
A new study finds that while blood transfusions for heart attack patients with anemia are commonly performed in emergency rooms, the practice can increase the risk of death when the transfusions are too extensive. The authors, led by Saurav Chatterjee, a
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By University of Texas M. D. Anderson Cancer Center
The U.S. Food and Drug Administration (FDA) this month expanded the options for patients with chronic myeloid leukemia and one form of acute lymphoblastic leukemia that carries the Philadelphia chromosome (Ph+ALL). It approved the drug ponatinib (Iclusig)
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By Frontiers
The rate of people who seek preventive cancer screenings has fallen over the last 10 years in the United States with wide variations between white-collar and blue-collar workers, according to a new study.
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By International Anesthesia Research Society (IARS)
At least two common gene variants are linked to "clinically meaningful" differences in pain scores in children after major surgery, a new study reports.
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By Johns Hopkins Medicine
Researchers have uncovered strong evidence that mice have a specific set of nerve cells that signal itch but not pain, a finding that may settle a decades-long debate about these sensations, and, if confirmed in humans, help in developing treatments for c
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By JAMA and Archives Journals
Depression in a group of U.S. Medicare recipients ages 65 years and older appears to be associated with prevalent mild cognitive impairment and an increased risk of dementia.
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By Rush University Medical Center
Researchers have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition.
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By Tufts University
Engineers have developed a new technique, called bioskiving. The fabrication process creates collagen structures from thin sheets of decellularized tendon stacked with alternating fiber directions that maintain much of collagen's natural strength.
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By Mount Sinai Medical Center
Nearly a third of children diagnosed with food allergies who participated in a recent study are bullied, according to researchers. Almost eight percent of children in the U.S. are allergic to foods such as peanuts, tree-nuts, milk, eggs, and shellfish.
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By Loyola University Health System
Getting out the boxes of holiday decorations from years gone by is a time-honored tradition. But in addition to stirring up memories, it also stirs up allergies.
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By JAMA and Archives Journals
Elevated levels of C-reactive protein, a marker of inflammatory disease, appear to be associated with increased risk of psychological distress and depression in the general population of adults in Denmark, according to a new study.
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By Washington University in St. Louis
Children suspected of having appendicitis are more likely to receive CT scans, which involve radiation, if they are evaluated at a general hospital, a new study has shown.
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By Massachusetts Eye and Ear Infirmary
Scientists have developed of HCENC-21 and HCEnC-21T, two novel model systems for human corneal endothelium.
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By JAMA and Archives Journals
An analysis of nationally representative survey data found significant improvement in the delivery of underused care, but more limited changes in the reduction of inappropriate care in ambulatory health care settings between 1998 and 2009.
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By New York University
Autistic-like behaviors can be partially remedied by normalizing excessive levels of protein synthesis in the brain, a team of researchers has found in a study of laboratory mice. The findings provide a pathway to the creation of pharmaceuticals aimed at
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By JAMA and Archives Journals
Children with chronic conditions increasingly used more resources in a group of children's hospitals compared with patients without a chronic condition, according to a report that analyzed data from 28 U.S. children's hospitals between 2004 and 2009.
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