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Discovery could eventually help diagnose and treat chronic pain 2013-01-25

By Brigham and Women's Hospital

More than 100 million Americans suffer from chronic pain. But treating and studying chronic pain is complex and presents many challenges. Scientists have long searched for a method to objectively measure pain and a new study advances that effort.

Research offers new targets for stroke treatments 2013-01-25

By University of Georgia

New research identifies the mechanisms responsible for regenerating blood vessels in the brain. Looking for ways to improve outcomes for stroke patients, researchers used candesartan, a commonly prescribed medication for lowering blood pressure, to identi

Lifestyle changes linked to better outcomes after peripheral intervention 2013-01-25

By University of Michigan Health System

Heart-healthy habits help patients with PAD, but lifestyle changes and medical therapy are dramatically underused by patients and their doctors.

Scientists create new approach to destroy disease-associated RNAs in cells 2013-01-25

By Scripps Research Institute

Scientists have developed a new approach to alter the function of RNA in living cells by designing molecules that recognize and disable RNA targets. As a proof of principle, in the new study the team designed a molecule that disabled the RNA causing myoto

Removing protein 'garbage' in nerve cells may help control 2 neurodegenerative diseases 2013-01-25

By Georgetown University Medical Center

A group of neuroscientists say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases -- amyotrophic lateral sclerosis, and frontotemporal dementia -- and, in the process, have uncovered a possible therapeut

Virtual reality and robotics in neurosurgery: Promise and challenges 2013-01-25

By Wolters Kluwer Health

Robotic technologies have the potential to help neurosurgeons perform precise, technically demanding operations, together with virtual reality environments to help them navigate through the brain, according to researchers.

MicroRNAs present exciting opportunities for cancer therapy and diagnosis 2013-01-25

By IOS Press

As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therap

Better stroke care, everywhere: Study boosts local hospitals' clotbuster use 2013-01-25

By University of Michigan Health System

From the moment a stroke occurs, patients must race against the clock to get treatment that can prevent lasting damage. Now, a new study shows the promise -- and the challenges -- of getting them state-of-the-art treatment safely at their local hospital,

New target for treating prediabetes in patients with kidney disease 2013-01-25

By American Society of Nephrology (ASN)

Insulin resistance, or prediabetes, in individuals with kidney disease may be caused by the progressive retention of certain compounds that are normally excreted by the kidneys in healthy individuals, according to a new study. The findings might be used t

Game-changing diagnostic and prognostic prostate cancer genetic tests developed 2013-01-25

By Thomas Jefferson University

Researchers have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers.

'Heart resilience' biomarker may help predict chemotherapy-induced cardiac damage earlier 2013-01-25

By Ohio State University Center for Clinical and Translational Science

Anthracyclines, a class of chemotherapy drugs commonly used to treat breast and childhood cancers are effective, but can cause heart damage that doesn't appear until long after treatment is over. By analyzing cardiac magnetic resonance imaging and heart h

Diabetes, blood pressure link to colon cancer recurrence, survival, research shows 2013-01-25

By Temple University Health System

A retrospective analysis of more than 36,000 patients with colon cancer showed that those with early stage disease and diabetes or high blood pressure -- two components of metabolic syndrome -- have a greater risk for cancer recurrence and of dying compar

Fine hands, fists of fury: Our hands evolved for punching, not just dexterity 2013-01-25

By University of Utah

Men whacked punching bags for a new study that suggests human hands evolved not only for the manual dexterity needed to use tools, play a violin or paint a work of art, but so men could make fists and fight.

Extending steroid treatment does not benefit children with hard-to-treat kidney disease, study finds 2013-01-25

By American Society of Nephrology (ASN)

Extending steroid treatment for the most common form of kidney disease in children provides no benefit for preventing relapses or side effects, according to a new study. The findings challenge previous assumptions about optimal treatment strategies for th

Rebuilding blood vessels through gene therapy 2013-01-25

By Weill Cornell Medical College

Diagnosed with severe coronary artery disease, a group of patients too ill for or not responding to other treatment options decided to take part in a clinical trial testing angiogenic gene therapy to help rebuild their damaged blood vessels.

Scientists discover new diagnostic markers for Kawasaki disease 2013-01-25

By EMBO - excellence in life sciences

Researchers have discovered proteins in human urine that offer new opportunities for the diagnosis, study and maybe even the treatment of Kawasaki disease. Mass spectrometry-based proteomic analysis of the human urine proteome, the entire set of proteins

New MRI analysis useful in predicting stroke complications caused by clot-busters 2013-01-25

By Johns Hopkins Medicine

Researchers have developed a new way of looking at standard MRI scans that more accurately measures damage to the blood-brain barrier in stroke victims, a process they hope will lead to safer, more individualized treatment of blood clots in the brain and

Pair of proteins gets brain cells into shape 2013-01-25

By Helmholtz Association of German Research Centres

Scientists have gained new insights into the early phase of the brain's development. Scientists have identified two proteins that control the formation of cell protuberances. The typical ramifications through which nerve cells receive and forward signals

New markers could improve treatment and survival in acute lymphoblastic leukemia 2013-01-25

By Basque Research

Acute lymphoblastic leukemia, the most common pediatric cancer, has been the subject of a new study. Newly identified genetic markers could improve the classification of risk groups and predict treatment toxicity in the patient.

Preventing prostate cancer through androgen deprivation may have harmful effects 2013-01-25

By American Association for Cancer Research

Mice deficient in PTEN in the prostate developed stable precancers. Androgen deprivation promoted progression to invasive prostate cancer. Patients with PTEN-deficient prostate precancers may not benefit from androgen deprivation chemoprevention therapy.

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