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Understanding the cellular patterns of development: Key mechanism in development involves 'paused' RNA polymerase 2013-01-25

By Stowers Institute for Medical Research

For a tiny embryo to grow into an entire fruit fly, mouse or human, the correct genes in each cell must turn on and off in precisely the right sequence. This intricate molecular dance produces the many parts of the whole creature, from muscles and skin to

New calculations solve an old problem with DNA 2013-01-25

By Université du Luxembourg

Normal DNA will switch to left-handed DNA when it is physically twisted, or when a lot of salt is added to the solution. Researchers were able to accurately calculate for the first time the amount of salt which is required to do this. Z-

miR-205 can be responsible for breast cancer 2013-01-25

By Versita

Scientists demonstrated that the microRNAs expression can be potentially responsible for the abnormal acini formation of breast cancer cells. They observed that the overexpression of the miR-205 influences the morphology of acini, linking this miRNA to br

Brain imaging insight into cannabis as a pain killer 2013-01-25

By University of Oxford

The pain relief offered by cannabis varies greatly between individuals, a brain imaging study suggests. The researchers found that an oral tablet of THC, the psychoactive ingredient in cannabis, tended to make the experience of pain more bearable, rather

Protein kinase Akt identified as arbiter of cancer stem cell fate 2013-01-25

By University of Pennsylvania School of Medicine

The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New research shows that Akt may be the key as to why cancer stem cells are so hard for the body to get rid of.

Gene expression improves the definition of a breast cancer subtype 2013-01-25

By Vall d´Hebron Institute of Oncology (VHIO)

Gene expression in breast cancer provides valuable biological information for better determining the diagnosis, treatment, risk of relapse and survival rate. However, the most common form of characterizing breast cancer is by histopathological techniques.

Cytomegalovirus: Scientists identify powerful infection strategy of widespread and potentially lethal virus 2013-01-25

By Gladstone Institutes

Scientists have mapped the molecular mechanism by which a virus known as cytomegalovirus so successfully infects its hosts. This discovery paves the way for new research avenues aimed at fighting this and other seemingly benign viruses that can turn deadl

Diabetes, blood pressure link to colon cancer recurrence, survival, research shows 2013-01-25

By Temple University Health System

A retrospective analysis of more than 36,000 patients with colon cancer showed that those with early stage disease and diabetes or high blood pressure -- two components of metabolic syndrome -- have a greater risk for cancer recurrence and of dying compar

Scientists discover new diagnostic markers for Kawasaki disease 2013-01-25

By EMBO - excellence in life sciences

Researchers have discovered proteins in human urine that offer new opportunities for the diagnosis, study and maybe even the treatment of Kawasaki disease. Mass spectrometry-based proteomic analysis of the human urine proteome, the entire set of proteins

Extending steroid treatment does not benefit children with hard-to-treat kidney disease, study finds 2013-01-25

By American Society of Nephrology (ASN)

Extending steroid treatment for the most common form of kidney disease in children provides no benefit for preventing relapses or side effects, according to a new study. The findings challenge previous assumptions about optimal treatment strategies for th

Virtual reality and robotics in neurosurgery: Promise and challenges 2013-01-25

By Wolters Kluwer Health

Robotic technologies have the potential to help neurosurgeons perform precise, technically demanding operations, together with virtual reality environments to help them navigate through the brain, according to researchers.

Game-changing diagnostic and prognostic prostate cancer genetic tests developed 2013-01-25

By Thomas Jefferson University

Researchers have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers.

Preventing prostate cancer through androgen deprivation may have harmful effects 2013-01-25

By American Association for Cancer Research

Mice deficient in PTEN in the prostate developed stable precancers. Androgen deprivation promoted progression to invasive prostate cancer. Patients with PTEN-deficient prostate precancers may not benefit from androgen deprivation chemoprevention therapy.

Asthmatics at increased risk of pulmonary embolism 2013-01-25

By European Lung Foundation

People with asthma have an increased risk of pulmonary embolism, according to new research.

Transplanted neural stem cells treat amyotrophic lateral sclerosis in mouse model 2013-01-25

By Sanford-Burnham Medical Research Institute

Transplanting neural stem cells into an ALS mouse model slows disease progression and prolongs survival. The transplanted neural stem cells changed the host environment for the better and protected endangered nerve cells. These findings demonstrate the po

Combo-snacks of cheese and vegetables cut kids calories, study suggests 2013-01-25

By Cornell Food & Brand Lab

A new study finds that serving children combined snacks of vegetables and cheese led them to eat 72 percent fewer calories -- and be just as satisfied as those who were served only potato chips.

Key gene for regenerating cells after heart attack 2013-01-25

By UT Southwestern Medical Center

Researchers have pinpointed a molecular mechanism needed to unleash the heart's ability to regenerate, a critical step toward developing eventual therapies for damage suffered following a heart attack.

New MRI analysis useful in predicting stroke complications caused by clot-busters 2013-01-25

By Johns Hopkins Medicine

Researchers have developed a new way of looking at standard MRI scans that more accurately measures damage to the blood-brain barrier in stroke victims, a process they hope will lead to safer, more individualized treatment of blood clots in the brain and

Pair of proteins gets brain cells into shape 2013-01-25

By Helmholtz Association of German Research Centres

Scientists have gained new insights into the early phase of the brain's development. Scientists have identified two proteins that control the formation of cell protuberances. The typical ramifications through which nerve cells receive and forward signals

Research into bleeding prevention post-birth could save lives 2013-01-25

By Bournemouth University

Research brings together evidence about the potential for misoprostol to prevent bleeding after home births in low resource countries.

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