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New technology will improve neuron activation induced by cochlear implants 2013-07-24

By Neural Regeneration Research

Cochlear implants, electrical prosthetic devices that stimulate inner ear neurons of individuals who have lost their cochlear sensory cells, restore usable hearing to deaf patients.

Endoplasmic reticulum: Scientists image 'parking garage' helix structure in protein-making factory 2013-07-22

By Cell Press

The endoplasmic reticulum is the protein-making factory within cells consisting of tightly stacked sheets of membrane studded with the molecules that make proteins. Now, researchers have refined a new microscopy imaging method to visualize exactly how the

Compound discovered at sea shows potency against anthrax 2013-07-22

By University of California - San Diego

Scientists have discovered anthracimycin, a new chemical compound from an ocean microbe that could one day set the stage for new treatments for anthrax and other ailments such as methicillin-resistant Staphylococcus aureus.

Thwarting protein production slows cancer cells' malignant march 2013-07-22

By Whitehead Institute for Biomedical Research

Protein production or translation is tightly coupled to a highly conserved stress response —- the heat shock response and its primary regulator, heat shock factor 1 (HSF1) —- that cancer cells rely on for survival and proliferation, ac

Genomic imprinting maintains a reserve pool of blood-forming stem cells in mouse bone marrow 2013-07-22

By Stowers Institute for Medical Research

Hematopoietic stem cells -- bone marrow-derived adult stem cells that give rise to the wide variety of specialized blood cells -- come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates s

How smoking increases vulnerability to alcohol abuse 2013-07-22

By Cell Press

Smoking is a well-known risk factor for subsequent alcohol abuse, but the mechanisms underlying this link are unknown. Now researchers show in a study conducted in rats that even a single exposure to nicotine temporarily changes how the brain's reward sys

A heart of gold: Gold nanofibers in engineered heart tissue can enhance electrical signalling 2013-07-22

By American Friends of Tel Aviv University

Scientists have integrated cardiac cells with nanofibers made of real gold particles to create functional engineered cardiac tissues. With the gold particles, these tissues contract much faster and stronger as a whole, he reports, making them more viable

Biochemical mapping helps explain who will respond to antidepressants 2013-07-22

By Duke Medicine

Researchers have identified biochemical changes in people taking antidepressants – but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine sy

Drug research: New technique shows if drugs have reached intended target 2013-07-22

By Nanyang Technological University

The search for new drugs, including those for cancer, is set to speed up thanks to a new research technique which could tell if drugs had reached their intended target.

Scientists construct visual of intracellular 'zip code' signaling linked to learning, memory 2013-07-22

By University of Vermont

New research provides a rare "picture" of the activity taking place at the single molecular level: visual evidence of the mechanisms involved when a cell transports mRNA (or messenger RNA) to where a protein is needed to perform a cellular funct

People with impaired glucose tolerance can show cognitive dysfunction 2013-07-22

By Institute of Food Technologists (IFT)

People with impaired glucose tolerance—the precursor to Type 2 diabetes—often show impaired cognitive function that may be alleviated through a diet designed specifically for their condition, according to new research.

Chemical compound shows promise as alternative to opioid pain relievers 2013-07-22

By The Mount Sinai Hospital / Mount Sinai School of Medicine

A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to new research.

Scientists show proof-of-principle for silencing extra chromosome responsible for Down syndrome 2013-07-22

By University of Massachusetts Medical School

Scientists have established that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment

Information in brain cells' electrical activity combines memory, environment, and state of mind 2013-07-22

By New York University

The information carried by the electrical activity of neurons is a mixture of stored memories, environmental circumstances, and current state of mind, scientists have found in a study of laboratory rats. The findings offer new insights into the neurobiolo

Infection biology: How Legionella subverts to survive 2013-07-22

By Ludwig-Maximilians-Universitaet Muenchen (LMU)

Bacteria of the genus Legionella have evolved a sophisticated system to replicate in the phagocytic cells of their hosts. Researchers have now identified a novel component of this system.

Chinese people may be at higher risk for stroke than Caucasians 2013-07-22

By American Academy of Neurology (AAN)

A new study suggests that Chinese people may be at higher risk for stroke than Caucasians.

Researcher finds way to convert blood cells into autoimmune disease treatment 2013-07-22

By Purdue University

Cells from one's own blood could be converted into a treatment for autoimmune diseases, like rheumatoid arthritis and Crohn's disease, thanks to new research.

Researchers target Achilles' heel of bacteria behind hospital-associated infections 2013-07-22

By Kansas State University

Researchers are defeating persistent bacteria known for causing infections in hospitals. They have discovered how a regulatory system helps this bacteria resist a host's innate immune defense -- a finding that may help develop novel drug compounds to figh

Self-perpetuating signals may drive tumor cells to spread 2013-07-22

By Johns Hopkins Medicine

Scientists have identified a self-perpetuating signaling circuit inside connective tissue cells that allows these cells to form a front and a back and propel themselves in a particular direction over a long period of time. This propulsion is the same move

New approach to treat the most common heart valve disease in Western countries 2013-07-22

By Montreal Heart Institute

Scientists have developed a new approach to treat aortic valve stenosis through the administration of a compound that prevents valve deterioration and can even reverse the progression of the disease. It is the most common type of heart valve disease in We

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